When you run powershell in exchange 2013 you see this error CategoryInfo : OpenError: (System.Manageme….
RemoteRunspace:RemoteRunspace) [New-PSSession], PSRemotingTransportException
+ FullyQualifiedErrorId : 1312,PSSessionOpenFailed
Exception calling “FindAll” with “0” argument(s): “Unknown error (0x80005000)”
You can block applications on your network from being run with something called a hash rule, these can be deployed with group policy. Here is a step by step guide on blocking applications on your network.